As an undergrad at UCSD’s Dept of Cognitive Science, I was deeply influenced by Gilles Fauconnier and am saddened to learn of his passing earlier this year. In revisting his landmark book, The Way We Think, I am excited to see just how much his notion of conceptual blending still resonates with my research. The figure below illustrates “double-scope integration”, in which two input conceptual frames are brought together into a blended frame that can lead to novel insights. This is what I aim to systematize with integrative modeling software – the capacity to blend models of different biological properties, and through their integration to reveal novel biology.